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Cantharidin increases the force of contraction and protein phosphorylation in isolated human atria

Cantharidin, an inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A), is known to increase the force of contraction and shorten the time to relaxation in human ventricular preparations. We hypothesized that cantharidin has similar positive inotropic effects in human right atria...

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Detalles Bibliográficos
Autores principales: Schwarz, R., Hofmann, B., Gergs, U., Neumann, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497697/
https://www.ncbi.nlm.nih.gov/pubmed/37097333
http://dx.doi.org/10.1007/s00210-023-02483-9