Cargando…

Unlocking the post-transplant microenvironment for successful islet function and survival

Islet transplantation (IT) offers the potential to restore euglycemia for patients with type 1 diabetes mellitus (T1DM). Despite improvements in islet isolation techniques and immunosuppressive regimes, outcomes remain suboptimal with UK five-year graft survivals (5YGS) of 55% and most patients stil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Doherty, Daniel T., Khambalia, Hussein A., van Dellen, David, Jennings, Rachel E., Piper Hanley, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497759/ https://www.ncbi.nlm.nih.gov/pubmed/37711891 http://dx.doi.org/10.3389/fendo.2023.1250126

Ejemplares similares

Kidney Transplantation From Hepatitis-C Viraemic Donors:Considerations for Practice in the United Kingdom
por: Doherty, Daniel T., et al.
Publicado: (2022)

The Influence of Microenvironment on Survival of Intraportal Transplanted Islets
por: Yan, Ling-ling, et al.
Publicado: (2022)

Role of Exosomes in Islet Transplantation
por: Mattke, Jordan, et al.
Publicado: (2021)

Donor insulin therapy in intensive care predicts early outcomes after pancreas transplantation
por: Shapey, Iestyn M., et al.
Publicado: (2021)

In Vivo Imaging of Transplanted Pancreatic Islets
por: Kim, Donghee, et al.
Publicado: (2018)

Kidney Transplantation From Donors With Acute Kidney Injury: Are the Concerns Justified? A Systematic Review and Meta-Analysis
por: Nita, George Emilian, et al.
Publicado: (2023)

Type I Interferon Is a Catastrophic Feature of the Diabetic Islet Microenvironment
por: Newby, Brittney N., et al.
Publicado: (2017)

Redox-Dependent Inflammation in Islet Transplantation Rejection
por: Barra, Jessie M., et al.
Publicado: (2018)

Advances in Pancreatic Islet Transplantation Sites for the Treatment of Diabetes
por: Cayabyab, Fritz, et al.
Publicado: (2021)

Amniotic Membrane Extract Protects Islets From Serum-Deprivation Induced Impairments and Improves Islet Transplantation Outcome
por: Yang, Zhaoming, et al.
Publicado: (2020)

Mouse models and human islet transplantation sites for intravital imaging
por: Wagner, Leslie E., et al.
Publicado: (2022)

The Eye as a Transplantation Site to Monitor Pancreatic Islet Cell Plasticity
por: Ilegems, Erwin, et al.
Publicado: (2021)

Adapting Protocols or Models for Use in Insulin-Requiring Diabetes and Islet Transplant Recipients
por: Ward, Glenn M., et al.
Publicado: (2021)

The Foundation for Engineering a Pancreatic Islet Niche
por: Patel, Smit N., et al.
Publicado: (2022)

Lessons from Human Islet Transplantation Inform Stem Cell-Based Approaches in the Treatment of Diabetes
por: Triolo, Taylor M., et al.
Publicado: (2021)

The role of GABA in islet function
por: Hagan, D. Walker, et al.
Publicado: (2022)

A Strategy to Simultaneously Cure Type 1 Diabetes and Diabetic Nephropathy by Transplant of Composite Islet-Kidney Grafts
por: Pomposelli, Thomas, et al.
Publicado: (2021)

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity
por: Peng, Xiao-Rong, et al.
Publicado: (2015)

Axon Guidance Molecules in the Islets of Langerhans
por: Waters, Bayley J., et al.
Publicado: (2022)

An Autonomous Cannabinoid System in Islets of Langerhans
por: Aseer, Kanikkai Raja, et al.
Publicado: (2021)

Erratum: The role of GABA in islet function
Publicado: (2023)

GABA signalling in human pancreatic islets
por: Jin, Zhe, et al.
Publicado: (2023)

GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk
por: He, Wei, et al.
Publicado: (2021)

miRNA-Mediated Immune Regulation in Islet Autoimmunity and Type 1 Diabetes
por: Scherm, Martin G., et al.
Publicado: (2020)

Islet Product Characteristics and Factors Related to Successful Human Islet Transplantation From the Collaborative Islet Transplant Registry (CITR) 1999–2010
por: Balamurugan, A N, et al.
Publicado: (2014)

In Vivo Imaging of Pancreatic Islet Grafts in Diabetes Treatment
por: Arifin, Dian R., et al.
Publicado: (2021)

Cilia Action in Islets: Lessons From Mouse Models
por: Cho, Jung Hoon, et al.
Publicado: (2022)

Transcriptional signature of islet neogenesis-associated protein peptide-treated rat pancreatic islets reveals induction of novel long non-coding RNAs
por: Romero, Agustín, et al.
Publicado: (2023)

Unlocking Sustained Innovation Success in Healthcare
por: McLaughlin, Gregory, et al.
Publicado: (2014)

Ontogeny of Neuro-Insular Complexes and Islets Innervation in the Human Pancreas
por: Proshchina, Alexandra E., et al.
Publicado: (2014)

Non-islet Cell Hypoglycemia: Case Series and Review of the Literature
por: Garla, Vishnu, et al.
Publicado: (2019)

Human Pluripotent Stem Cells to Model Islet Defects in Diabetes
por: Balboa, Diego, et al.
Publicado: (2021)

Screening and Identification of Key Genes for Activation of Islet Stellate Cell
por: Wang, Xiaohang, et al.
Publicado: (2021)

Smartphone-microfluidic fluorescence imaging system for studying islet physiology
por: Yu, Xiaoyu, et al.
Publicado: (2022)

Small molecule glucagon release inhibitors with activity in human islets
por: Kalwat, Michael A., et al.
Publicado: (2023)

Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress
por: Witkowski, Piotr, et al.
Publicado: (2022)

Clinical Diversity in Focal Congenital Hyperinsulinism in Infancy Correlates With Histological Heterogeneity of Islet Cell Lesions
por: Craigie, Ross J., et al.
Publicado: (2018)

Functional Characterization of the Human Islet Microvasculature Using Living Pancreas Slices
por: Mateus Gonçalves, Luciana, et al.
Publicado: (2021)

In Vivo and In Situ Approach to Study Islet Microcirculation: A Mini-Review
por: Dybala, Michael P., et al.
Publicado: (2021)

In vitro assessment of pancreatic hormone secretion from isolated porcine islets
por: Mourad, Nizar I., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_922rr3fjqlvbn0timj3gu5bgib