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Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancer

Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) is an immune checkpoint regulator exclusively expressed on T cells that obstructs the cell’s effector functions. Ipilimumab (Yervoy®), a CTLA-4 blocking antibody, emerged as a notable breakthrough in modern cancer treatment, showing upfront clinic...

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Detalles Bibliográficos
Autores principales:	Bulaon, Christine Joy I., Khorattanakulchai, Narach, Rattanapisit, Kaewta, Sun, Hongyan, Pisuttinusart, Nuttapat, Strasser, Richard, Tanaka, Shiho, Soon-Shiong, Patrick, Phoolcharoen, Waranyoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497774/ https://www.ncbi.nlm.nih.gov/pubmed/37711295 http://dx.doi.org/10.3389/fpls.2023.1149455

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