Cargando…

Mechanism of RBBP8‐mediated homologous recombination repair in gastric cancer synthetic lethal

BACKGROUND: It is of great clinical significance to further explore new strategies and potential combined therapeutic targets for gastric cancer. This study aimed to investigate the synthetic lethal effect of RBBP8 molecular intervention combined with a poly ADP ribose polymerase (PARP) inhibitor in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Yang, Wang, Shuxia, Yin, Yanhua, Wang, Guangsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497805/ https://www.ncbi.nlm.nih.gov/pubmed/37711862 http://dx.doi.org/10.1002/cdt3.75

Ejemplares similares

Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality
por: Sanese, Paola, et al.
Publicado: (2020)

Prognosis value of RBBP8 expression in plasma cell myeloma
por: Zhang, Weilong, et al.
Publicado: (2019)

The mechanism of radiotherapy for lung adenocarcinoma in promoting protein SIRT6-mediated deacetylation of RBBP8 to enhance the sensitivity of targeted therapy
por: Wang, Jiying, et al.
Publicado: (2022)

DNA repair and synthetic lethality
por: Guo, Gong-she, et al.
Publicado: (2011)

Prognostic value of CtIP/RBBP8 expression in breast cancer
por: Soria-Bretones, Isabel, et al.
Publicado: (2013)

CRISPR screen identifies the role of RBBP8 in mediating unfolded protein response induced liver damage through regulating protein synthesis
por: Wang, Heting, et al.
Publicado: (2023)

Targeting Homologous Recombination Deficiency in Ovarian Cancer with PARP Inhibitors: Synthetic Lethal Strategies That Impact Overall Survival
por: Xie, Tao, et al.
Publicado: (2022)

RBBP4 Enhances Platinum Chemo Resistance in Lung Adenocarcinoma
por: Wang, Nianwu, et al.
Publicado: (2021)

Analysis of repair mechanism choice during homologous recombination
por: Agmon, Neta, et al.
Publicado: (2009)

Homologous Recombination Repair Mechanisms in Serous Endometrial Cancer
por: Jönsson, Jenny-Maria, et al.
Publicado: (2021)

Rbbp4 Suppresses Premature Differentiation of Embryonic Stem Cells
por: Huang, Yikai, et al.
Publicado: (2021)

AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress
por: Villafañez, Florencia, et al.
Publicado: (2019)

A PHF8 Homolog in C. elegans Promotes DNA Repair via Homologous Recombination
por: Lee, Changrim, et al.
Publicado: (2015)

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality
por: Jacunski, Alexandra, et al.
Publicado: (2015)

Hypoxia-induced RBBP7 promotes esophagus cancer progression by inducing CDK4 expression: RBBP7 promotes esophagus cancer progression
por: Wang, Renfeng, et al.
Publicado: (2022)

PRPF8 is important for BRCA1-mediated homologous recombination
por: Onyango, David O., et al.
Publicado: (2017)

ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair
por: Chen, Guo, et al.
Publicado: (2018)

Evolving DNA repair synthetic lethality targets in cancer
por: Kulkarni, Sanat, et al.
Publicado: (2022)

Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair
por: Ceccaldi, Raphael, et al.
Publicado: (2015)

TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair
por: Hariharasudhan, Gurusamy, et al.
Publicado: (2022)

A plant-specific module for homologous recombination repair
por: Wang, Xuanpeng, et al.
Publicado: (2022)

Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation
por: Chen, Wei-Ting, et al.
Publicado: (2021)

ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
por: Xu, Shibin, et al.
Publicado: (2021)

Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer
por: Mijnes, Jolein, et al.
Publicado: (2018)

Homologous Recombination Repair Polymorphisms and the Risk for Osteosarcoma
por: Goričar, Katja, et al.
Publicado: (2015)

Leveraging homologous recombination repair deficiency in sarcoma
por: Slade, Dea, et al.
Publicado: (2023)

The C. elegans Homolog of RBBP6 (RBPL-1) Regulates Fertility through Controlling Cell Proliferation in the Germline and Nutrient Synthesis in the Intestine
por: Huang, Ping, et al.
Publicado: (2013)

Single nucleotide polymorphisms of nucleotide excision repair and homologous recombination repair pathways and their role in the risk of osteosarcoma
por: Jin, Guojun, et al.
Publicado: (2015)

Ctf18 is required for homologous recombination-mediated double-strand break repair
por: Ogiwara, Hideaki, et al.
Publicado: (2007)

X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells
por: De Vitis, Marco, et al.
Publicado: (2019)

Srs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa
por: Suzuki, Keiichiro, et al.
Publicado: (2005)

Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors
por: Hu, Changkun, et al.
Publicado: (2022)

Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib
por: Bagnolini, Greta, et al.
Publicado: (2020)

RBBP7 is a prognostic biomarker in patients with esophageal squamous cell carcinoma
por: Yu, Ning, et al.
Publicado: (2018)

Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy
por: Wang, Yicun, et al.
Publicado: (2022)

Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer
por: Hao, Suisui, et al.
Publicado: (2022)

The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination
por: van den Tempel, Nathalie, et al.
Publicado: (2017)

DEK is required for homologous recombination repair of DNA breaks
por: Smith, Eric A., et al.
Publicado: (2017)

Homologous Recombination Repair Deficiency and Implications for Tumor Immunogenicity
por: van Wilpe, Sandra, et al.
Publicado: (2021)

Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators
por: McLellan, Jessica L., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_17sck9jq16dgbve66etn04vmiq