Deficiency for scavenger receptors Stabilin‐1 and Stabilin‐2 leads to age‐dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice

Stabilin‐1 (Stab1) and Stabilin‐2 (Stab2) are two major scavenger receptors of liver sinusoidal endothelial cells that mediate removal of diverse molecules from the plasma. Double‐knockout mice (Stab‐DKO) develop impaired kidney function and a decreased lifespan, while single Stabilin deficiency or...

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Detalles Bibliográficos
Autores principales: Leibing, Thomas, Riedel, Anna, Xi, Yannick, Adrian, Monica, Krzistetzko, Jessica, Kirkamm, Christof, Dormann, Christof, Schledzewski, Kai, Goerdt, Sergij, Géraud, Cyrill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497815/
https://www.ncbi.nlm.nih.gov/pubmed/37357460
http://dx.doi.org/10.1111/acel.13914

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