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Releasing YAP dysfunction‐caused replicative toxicity rejuvenates mesenchymal stem cells

Hippo‐independent YAP dysfunction has been demonstrated to cause chronological aging of stromal cells by impairing the integrity of nuclear envelope (NE). In parallel with this report, we uncover that YAP activity also controls another type of cellular senescence, the replicative senescence in in vi...

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Detalles Bibliográficos
Autores principales: Yu, Fanyuan, Yao, Lin, Li, Feifei, Wang, Chenglin, Ye, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497818/
https://www.ncbi.nlm.nih.gov/pubmed/37340571
http://dx.doi.org/10.1111/acel.13913

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