Cargando…

Causal associations of sarcopenia‐related traits with cardiometabolic disease and Alzheimer's disease and the mediating role of insulin resistance: A Mendelian randomization study

The causal influence of sarcopenia on cardiometabolic disease and Alzheimer's disease and whether and to what extent insulin resistance plays a mediating role therein were unclear. We performed two‐step, two‐sample Mendelian randomization applying genetic instruments of sarcopenia‐related trait...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Chaojie, Kong, Lijie, Wang, Yiying, Zheng, Jie, Xu, Min, Xu, Yu, Li, Mian, Zhao, Zhiyun, Lu, Jieli, Chen, Yuhong, Wang, Weiqing, Ning, Guang, Bi, Yufang, Wang, Tiange
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497819/ https://www.ncbi.nlm.nih.gov/pubmed/37403750 http://dx.doi.org/10.1111/acel.13923

Ejemplares similares

Independent Associations of Education, Intelligence, and Cognition With Hypertension and the Mediating Effects of Cardiometabolic Risk Factors: A Mendelian Randomization Study
por: Wang, Yiying, et al.
Publicado: (2022)

Causal Effect of Relative Carbohydrate Intake on Hypertension through Psychological Well-Being and Adiposity: A Mendelian Randomization Study
por: Ye, Chaojie, et al.
Publicado: (2023)

SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study
por: Xu, Min, et al.
Publicado: (2022)

Hypertriglyceridemic hyperapoB and the development and resolution of nonalcoholic fatty liver disease: a cohort study
por: Wang, Yiying, et al.
Publicado: (2023)

Causal Association Between Obesity, Circulating Glutamine Levels, and Depression: A Mendelian Randomization Study
por: He, Ruixin, et al.
Publicado: (2022)

Mendelian Randomization Analysis Support Causal Associations of HbA1c with Circulating Triglyceride, Total and Low-density Lipoprotein Cholesterol in a Chinese Population
por: Jia, Xu, et al.
Publicado: (2019)

Additional Cover
por: Ye, Chaojie, et al.
Publicado: (2023)

Comprehensive risk profiles of family history and lifestyle and metabolic risk factors in relation to diabetes: A prospective cohort study
por: Ye, Chaojie, et al.
Publicado: (2022)

Dissecting the causal effect between gut microbiota, DHA, and urate metabolism: A large-scale bidirectional Mendelian randomization
por: Hou, Tianzhichao, et al.
Publicado: (2023)

Dissecting Causal Relationships Between Gut Microbiota, Blood Metabolites, and Stroke: A Mendelian Randomization Study
por: Wang, Qi, et al.
Publicado: (2023)

Genetic susceptibility, family history of diabetes and healthy lifestyle factors in relation to diabetes: A gene–environment interaction analysis in Chinese adults
por: Ye, Chaojie, et al.
Publicado: (2021)

Associations of body shapes with insulin resistance and cardiometabolic risk in middle-aged and elderly Chinese
por: Zhou, Yulin, et al.
Publicado: (2021)

Association between mid-upper arm circumference and cardiometabolic risk in Chinese population: a cross-sectional study
por: Hou, Yanan, et al.
Publicado: (2019)

Association of Early and Supernormal Vascular Aging categories with cardiovascular disease in the Chinese population
por: Cao, Qiuyu, et al.
Publicado: (2022)

Association of QTc Interval with Risk of Cardiovascular Diseases and Related Vascular Traits: A Prospective and Longitudinal Analysis
por: Deng, Chanjuan, et al.
Publicado: (2020)

Association of Bisphenol A Exposure With Hypertension and Early Macrovascular Diseases in Chinese Adults: A Cross-Sectional Study
por: Wang, Tiange, et al.
Publicado: (2015)

Evaluating the Effects of Omega-3 Polyunsaturated Fatty Acids on Inflammatory Bowel Disease via Circulating Metabolites: A Mediation Mendelian Randomization Study
por: Jia, Xiaojing, et al.
Publicado: (2023)

Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals
por: Dai, Huajie, et al.
Publicado: (2021)

The Association and Predictive Ability of ECG Abnormalities with Cardiovascular Diseases: A Prospective Analysis
por: Niu, Jingya, et al.
Publicado: (2020)

Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation
por: Huang, Xiaolin, et al.
Publicado: (2016)

Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study
por: Zheng, Jie, et al.
Publicado: (2023)

Association between serum LDL‐C concentrations and risk of diabetes: A prospective cohort study
por: Huang, Jiaojiao, et al.
Publicado: (2023)

Arterial Stiffness, Biomarkers of Liver Fat, and the Development of Metabolic Dysfunction in Metabolically Healthy Population: A Prospective Study
por: Lin, Lin, et al.
Publicado: (2022)

Type 2 Diabetes, Diabetes Genetic Score and Risk of Decreased Renal Function and Albuminuria: A Mendelian Randomization Study
por: Xu, Min, et al.
Publicado: (2016)

Age-specific prevalence, subtypes and risk factors of metabolic diseases in Chinese adults and the different patterns from other racial/ethnic populations
por: Cao, Qiuyu, et al.
Publicado: (2022)

Evaluating the distinct pleiotropic effects of omega-3 fatty acids on type 2 diabetes mellitus: a mendelian randomization study
por: Hu, Chunyan, et al.
Publicado: (2023)

Fruit intake, genetic risk and type 2 diabetes: a population-based gene–diet interaction analysis
por: Jia, Xu, et al.
Publicado: (2021)

New clusters of serum electrolytes aid in stratification of diabetes and metabolic risk
por: Hou, Yanan, et al.
Publicado: (2021)

Sex differences in the risk of arterial stiffness among adults with different glycemic status and modifications by age
por: Zhang, Xiaoyun, et al.
Publicado: (2023)

Sex- and age-specific association between outdoor light at night and obesity in Chinese adults: A national cross-sectional study of 98,658 participants from 162 study sites
por: Zhang, Xiaoyun, et al.
Publicado: (2023)

Roles of gut microbiota in atrial fibrillation: insights from Mendelian randomization analysis and genetic data from over 430,000 cohort study participants
por: Dai, Huajie, et al.
Publicado: (2023)

Circulating Prolactin Associates With Diabetes and Impaired Glucose Regulation: A population-based study
por: Wang, Tiange, et al.
Publicado: (2013)

Nonalcoholic fatty liver disease in relation to the remission and progression along the glycemic continuum
por: Xin, Zhuojun, et al.
Publicado: (2022)

Pan‐risk factor for a comprehensive cardiovascular health management
por: Zheng, Ruizhi, et al.
Publicado: (2022)

Serum lipoprotein (a) associates with a higher risk of reduced renal function: a prospective investigation
por: Xuan, Liping, et al.
Publicado: (2020)

Risk of subclinical atherosclerosis across metabolic transition in individuals with or without fatty liver disease: a prospective cohort study
por: Xin, Zhuojun, et al.
Publicado: (2023)

Individual and Combined Associations of Glucose Metabolic Components With Cognitive Function Modified by Obesity
por: He, Ruixin, et al.
Publicado: (2021)

Long-Term Glycemic Variability Is Associated With Arterial Stiffness in Chinese Adults
por: Zhang, Yuwen, et al.
Publicado: (2021)

Visit‑to‑visit blood pressure variability is associated with arterial stiffness in Chinese adults: A prospective analysis
por: Zhang, Yuwen, et al.
Publicado: (2021)

Age-specific difference in the association between prediabetes and subclinical atherosclerosis: an analysis of a chinese prospective cohort study
por: Cao, Qiuyu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ro5tc1vrtgrum7uclm5fq4vms4