Identification and functional validation of an enhancer variant in the 9p21.3 locus associated with glaucoma risk and elevated expression of p16(INK4a)

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Glaucoma is a leading cause of irreversible blindness, with advanced age being the single most significant risk factor. However, the mechanisms underlying the relationship between aging and glaucoma remain unclear. Genome‐wide association studies (GWAS) have successfully identified genetic variants...

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Detalles Bibliográficos
Autores principales: Zhu, Yizhou, Tazearslan, Cagdas, Rosenfeld, Michael G., Fiser, Andras, Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497822/
https://www.ncbi.nlm.nih.gov/pubmed/37345431
http://dx.doi.org/10.1111/acel.13908
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