The role of aging and brain‐derived neurotrophic factor signaling in expression of base excision repair genes in the human brain

DNA damage is a central contributor to the aging process. In the brain, a major threat to the DNA is the considerable amount of reactive oxygen species produced, which can inflict oxidative DNA damage. This type of damage is removed by the base excision repair (BER) pathway, an essential DNA repair...

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Detalles Bibliográficos
Autores principales: Lautrup, Sofie, Myrup Holst, Camilla, Yde, Anne, Asmussen, Stine, Thinggaard, Vibeke, Larsen, Knud, Laursen, Lisbeth Schmidt, Richner, Mette, Vægter, Christian B., Prieto, G. Aleph, Berchtold, Nicole, Cotman, Carl W., Stevnsner, Tinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497833/
https://www.ncbi.nlm.nih.gov/pubmed/37334527
http://dx.doi.org/10.1111/acel.13905

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