Sex‐ and APOE‐specific genetic risk factors for late‐onset Alzheimer's disease: Evidence from gene–gene interaction of longevity‐related loci

Advanced age is the largest risk factor for late‐onset Alzheimer's disease (LOAD), a disease in which susceptibility correlates to almost all hallmarks of aging. Shared genetic signatures between LOAD and longevity were frequently hypothesized, likely characterized by distinctive epistatic and...

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Detalles Bibliográficos
Autores principales: Dato, Serena, De Rango, Francesco, Crocco, Paolina, Pallotti, Stefano, Belloy, Michael E., Le Guen, Yann, Greicius, Michael D., Passarino, Giuseppe, Rose, Giuseppina, Napolioni, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497850/
https://www.ncbi.nlm.nih.gov/pubmed/37621137
http://dx.doi.org/10.1111/acel.13938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497850/
https://www.ncbi.nlm.nih.gov/pubmed/37621137
http://dx.doi.org/10.1111/acel.13938

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