The World of GPCR dimers – Mapping dopamine receptor D(2) homodimers in different activation states and configuration arrangements

G protein-coupled receptors (GPCRs) are known to dimerize, but the molecular and structural basis of GPCR dimers is not well understood. In this study, we developed a computational framework to generate models of symmetric and asymmetric GPCR dimers using different monomer activation states and iden...

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Detalles Bibliográficos
Autores principales: Bueschbell, Beatriz, Magalhães, Pedro R., Barreto, Carlos A.V., Melo, Rita, Schiedel, Anke C., Machuqueiro, Miguel, Moreira, Irina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497915/
https://www.ncbi.nlm.nih.gov/pubmed/37711187
http://dx.doi.org/10.1016/j.csbj.2023.08.032

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