Impaired aldehyde detoxification exacerbates motor deficits in an alpha‐synuclein mouse model of Parkinson's disease

INTRODUCTION: The discovery of biogenic aldehydes in the postmortem parkinsonian brain and the ability of these aldehydes to modify and cross‐link proteins has called attention to their possible role in Parkinson's disease. For example, many in vitro studies have found that the aldehyde metabol...

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Detalles Bibliográficos
Autores principales: Martinez, Paul Anthony, Martinez, Vanessa Elia, Rani, Sheela, Murrell, Meredith, Javors, Martin, Gelfond, Jonathan, Doorn, Jonathan Alan, Fernandez, Elizabeth, Strong, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498093/
https://www.ncbi.nlm.nih.gov/pubmed/37452461
http://dx.doi.org/10.1002/brb3.3150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498093/
https://www.ncbi.nlm.nih.gov/pubmed/37452461
http://dx.doi.org/10.1002/brb3.3150

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