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Impaired aldehyde detoxification exacerbates motor deficits in an alpha‐synuclein mouse model of Parkinson's disease
INTRODUCTION: The discovery of biogenic aldehydes in the postmortem parkinsonian brain and the ability of these aldehydes to modify and cross‐link proteins has called attention to their possible role in Parkinson's disease. For example, many in vitro studies have found that the aldehyde metabol...
Autores principales: | Martinez, Paul Anthony, Martinez, Vanessa Elia, Rani, Sheela, Murrell, Meredith, Javors, Martin, Gelfond, Jonathan, Doorn, Jonathan Alan, Fernandez, Elizabeth, Strong, Randy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498093/ https://www.ncbi.nlm.nih.gov/pubmed/37452461 http://dx.doi.org/10.1002/brb3.3150 |
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