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pH-Sensitive nanodiamond co-delivery of retinal and doxorubicin boosts breast cancer chemotherapy
Herein for the first time we take the advantage of nanodiamonds (NDs) to covalently immobilize all-trans retinal (NPA) by an imine bond, allowing pH-mediated drug release. DOX is then physically adsorbed onto NPA to form an NPA@D co-loaded double drug in the sodium citrate medium, which is also susc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498152/ https://www.ncbi.nlm.nih.gov/pubmed/37711368 http://dx.doi.org/10.1039/d3ra03907b |