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pH-Sensitive nanodiamond co-delivery of retinal and doxorubicin boosts breast cancer chemotherapy

Herein for the first time we take the advantage of nanodiamonds (NDs) to covalently immobilize all-trans retinal (NPA) by an imine bond, allowing pH-mediated drug release. DOX is then physically adsorbed onto NPA to form an NPA@D co-loaded double drug in the sodium citrate medium, which is also susc...

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Detalles Bibliográficos
Autores principales: Cui, Jicheng, Hu, Bo, Fu, Yuejun, Xu, Zhengkun, Li, Yingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498152/
https://www.ncbi.nlm.nih.gov/pubmed/37711368
http://dx.doi.org/10.1039/d3ra03907b