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Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis

Human liver tissue is composed of heterogeneous mixtures of different cell types and their cellular stoichiometry can provide information on hepatic physiology and disease progression. Deconvolution algorithms for the identification of cell types and their proportions have recently been developed fo...

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Detalles Bibliográficos
Autores principales: Handin, Niklas, Yuan, Di, Ölander, Magnus, Wegler, Christine, Karlsson, Cecilia, Jansson-Löfmark, Rasmus, Hjelmesæth, Jøran, Åsberg, Anders, Lauschke, Volker M., Artursson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498185/
https://www.ncbi.nlm.nih.gov/pubmed/37711184
http://dx.doi.org/10.1016/j.csbj.2023.08.037