Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood. METHODS: Circular RNA hsa_circ_0001681 (termed Circ-RAPGEF5 hereafter) was...

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Detalles Bibliográficos
Autores principales: Zheng, Junhao, Wang, Yali, Tao, Liye, Cai, Jingwei, Shen, Zefeng, Liu, Yang, Pan, Haoyu, Li, Shihao, Ruan, Yeling, Chen, Tianyi, Ye, Zhengtao, Lin, Kainan, Sun, Yin, Xu, Junjie, Liang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498551/
https://www.ncbi.nlm.nih.gov/pubmed/37705041
http://dx.doi.org/10.1186/s13046-023-02813-y

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