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A robust deep learning workflow to predict CD8 + T-cell epitopes

BACKGROUND: T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the development of various T-cell-focused immunotherapies. However, the identification of...

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Detalles Bibliográficos
Autores principales: Lee, Chloe H., Huh, Jaesung, Buckley, Paul R., Jang, Myeongjun, Pinho, Mariana Pereira, Fernandes, Ricardo A., Antanaviciute, Agne, Simmons, Alison, Koohy, Hashem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498576/
https://www.ncbi.nlm.nih.gov/pubmed/37705109
http://dx.doi.org/10.1186/s13073-023-01225-z