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Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins

BACKGROUND: The molecular pathology of diffuse large B cell lymphoma (DLBCL) has been extensively studied. Among DLBCL subtypes, the prognosis of CD5-positive DLBCL is worse than that of CD5-negative DLBCL, considering the central nervous system relapse and poor response to R-CHOP therapy. However,...

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Detalles Bibliográficos
Autores principales: Hiratsuka, Takuya, Ito, Shinji, Sakai, Rika, Yokose, Tomoyuki, Endo, Tatsuya, Daigo, Yataro, Miyagi, Yohei, Tsuruyama, Tatsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498596/
https://www.ncbi.nlm.nih.gov/pubmed/37705009
http://dx.doi.org/10.1186/s12014-023-09422-z