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Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study
BACKGROUND: Enucleation, a surgical procedure, is commonly used to treat large jaw cysts, unicystic ameloblastomas and keratocysts. However, it remains unclear to what extent the jaw bone regenerates after enucleation. We aimed to evaluate the percentage and the survival analysis of jaw bone regener...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498605/ https://www.ncbi.nlm.nih.gov/pubmed/37704975 http://dx.doi.org/10.1186/s12903-023-03307-1 |
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author | Al-Qurmoti, Sarah Mahyoub, Mueataz A. Elhoumed, Mohamed Al-Moraissi, Essam Ahmed Tao, Zhuo‑Ying Hou, Xiaoru Li, Jing Bi, Sisi Wu, Haiyan Zhang, Jing Lv, Huanhuan Jiao, Lina Al-Karmati, Sokina Acharya, Kiran Hu, Xiaoyi Li, Jinfeng |
author_facet | Al-Qurmoti, Sarah Mahyoub, Mueataz A. Elhoumed, Mohamed Al-Moraissi, Essam Ahmed Tao, Zhuo‑Ying Hou, Xiaoru Li, Jing Bi, Sisi Wu, Haiyan Zhang, Jing Lv, Huanhuan Jiao, Lina Al-Karmati, Sokina Acharya, Kiran Hu, Xiaoyi Li, Jinfeng |
author_sort | Al-Qurmoti, Sarah |
collection | PubMed |
description | BACKGROUND: Enucleation, a surgical procedure, is commonly used to treat large jaw cysts, unicystic ameloblastomas and keratocysts. However, it remains unclear to what extent the jaw bone regenerates after enucleation. We aimed to evaluate the percentage and the survival analysis of jaw bone regeneration, in terms of cavity volume residual (CVR), in patients who underwent enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts. METHODS: We collected data longitudinally from 75 patients who underwent jaw cystic lesions enucleation at the Stomatological Hospital of Xi’an Jiaotong University, between January 2015 and June 2021. All patients had both preoperative and postoperative cone-beam computed tomography (CBCT) imaging data. CBCT images were analyzed using Image J. Changes in the CVR were assessed at various follow-up time points, and the Kaplan-Meier method was utilized to evaluate the CVR over time. RESULTS: The patients had a mean age of 31.7 years (range: 5.5–72 years) with 58.66% of them being male. The postoperative CVR was 32.20% at three months, 21.10% at six months, 15.90% at 12 months, and 5.60% at 24 months. The percentage of CVR during follow-up periods for the initial size Quartile (Q)1 (212.54-1569.60 mm(3)) was substantially lower than those of Q2 and Q3 at and after seven months of follow-up and became statistically significant at the 12-month mark. CONCLUSION: This study demonstrates that spontaneous bone regeneration can occur after enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts, even without the use of filler materials. The initial size of the lesion had a significant impact on the outcome of cystic lesion enucleation over time. To minimize the risks associated with radiation exposure and expenses, we recommend reducing the frequency of CT imaging follow-ups for patients with small initial cavity sizes (ranging from 212.54 to 1569.60 mm(3)). |
format | Online Article Text |
id | pubmed-10498605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104986052023-09-14 Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study Al-Qurmoti, Sarah Mahyoub, Mueataz A. Elhoumed, Mohamed Al-Moraissi, Essam Ahmed Tao, Zhuo‑Ying Hou, Xiaoru Li, Jing Bi, Sisi Wu, Haiyan Zhang, Jing Lv, Huanhuan Jiao, Lina Al-Karmati, Sokina Acharya, Kiran Hu, Xiaoyi Li, Jinfeng BMC Oral Health Research BACKGROUND: Enucleation, a surgical procedure, is commonly used to treat large jaw cysts, unicystic ameloblastomas and keratocysts. However, it remains unclear to what extent the jaw bone regenerates after enucleation. We aimed to evaluate the percentage and the survival analysis of jaw bone regeneration, in terms of cavity volume residual (CVR), in patients who underwent enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts. METHODS: We collected data longitudinally from 75 patients who underwent jaw cystic lesions enucleation at the Stomatological Hospital of Xi’an Jiaotong University, between January 2015 and June 2021. All patients had both preoperative and postoperative cone-beam computed tomography (CBCT) imaging data. CBCT images were analyzed using Image J. Changes in the CVR were assessed at various follow-up time points, and the Kaplan-Meier method was utilized to evaluate the CVR over time. RESULTS: The patients had a mean age of 31.7 years (range: 5.5–72 years) with 58.66% of them being male. The postoperative CVR was 32.20% at three months, 21.10% at six months, 15.90% at 12 months, and 5.60% at 24 months. The percentage of CVR during follow-up periods for the initial size Quartile (Q)1 (212.54-1569.60 mm(3)) was substantially lower than those of Q2 and Q3 at and after seven months of follow-up and became statistically significant at the 12-month mark. CONCLUSION: This study demonstrates that spontaneous bone regeneration can occur after enucleation of large jaw cysts, unicystic ameloblastomas and keratocysts, even without the use of filler materials. The initial size of the lesion had a significant impact on the outcome of cystic lesion enucleation over time. To minimize the risks associated with radiation exposure and expenses, we recommend reducing the frequency of CT imaging follow-ups for patients with small initial cavity sizes (ranging from 212.54 to 1569.60 mm(3)). BioMed Central 2023-09-13 /pmc/articles/PMC10498605/ /pubmed/37704975 http://dx.doi.org/10.1186/s12903-023-03307-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Al-Qurmoti, Sarah Mahyoub, Mueataz A. Elhoumed, Mohamed Al-Moraissi, Essam Ahmed Tao, Zhuo‑Ying Hou, Xiaoru Li, Jing Bi, Sisi Wu, Haiyan Zhang, Jing Lv, Huanhuan Jiao, Lina Al-Karmati, Sokina Acharya, Kiran Hu, Xiaoyi Li, Jinfeng Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title | Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title_full | Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title_fullStr | Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title_full_unstemmed | Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title_short | Volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
title_sort | volumetric reduction in large cystic jaw lesions postoperative enucleation: a longitudinal clinical study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498605/ https://www.ncbi.nlm.nih.gov/pubmed/37704975 http://dx.doi.org/10.1186/s12903-023-03307-1 |
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