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Nitrilium ion trapping as a strategy to access structurally diverse heterobiaryl-containing peptide macrocycles
Biaryl and heterobiaryl-containing cyclic peptides represent promising scaffolds for the development of bioactive molecules. The incorporation of heterobiaryl motifs continues to pose synthetic challenges, which is partially due to the difficulties in effecting late-stage metal-catalyzed cross-coupl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498670/ https://www.ncbi.nlm.nih.gov/pubmed/37712035 http://dx.doi.org/10.1039/d3sc03058j |