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The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients

OBJECTIVE: Geriatric patients have more complicated appendicitis, which leads to higher morbidity and mortality rates. Sarcopenia has been shown to have a negative impact on patients undergoing surgery. This study aims to reveal the predictive value of computerized tomography‐assessed (CT‐assessed)...

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Autores principales: Yildirim, Ali Cihat, Atlanoğlu, Şahinde, Gedik, Mehmet Ali, Zeren, Sezgin, Ekici, Mehmet Fatih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498833/
https://www.ncbi.nlm.nih.gov/pubmed/37711261
http://dx.doi.org/10.1002/agm2.12259
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author Yildirim, Ali Cihat
Atlanoğlu, Şahinde
Gedik, Mehmet Ali
Zeren, Sezgin
Ekici, Mehmet Fatih
author_facet Yildirim, Ali Cihat
Atlanoğlu, Şahinde
Gedik, Mehmet Ali
Zeren, Sezgin
Ekici, Mehmet Fatih
author_sort Yildirim, Ali Cihat
collection PubMed
description OBJECTIVE: Geriatric patients have more complicated appendicitis, which leads to higher morbidity and mortality rates. Sarcopenia has been shown to have a negative impact on patients undergoing surgery. This study aims to reveal the predictive value of computerized tomography‐assessed (CT‐assessed) sarcopenia for complicated appendicitis in geriatric patients. METHODS: One‐hundred fifty‐four patients’ with acute appendicitis age, gender, co‐morbidities, appendicitis status, and body mass index (BMI) values were analyzed. The skeletal muscle index (SMI) and related measurements were evaluated. RESULTS: Fifty‐two percent of the patients had complicated, and 48% had uncomplicated appendicitis. There was a statistically significant difference between uncomplicated and complicated cases regarding BMI, SMI, and muscle area values (P < 0.05). The cutoff point by Receiver Operating Characteristic Curve analysis was conducted for SMI and showed 71% sensitivity and 52% specificity (P = 0.042). Multivariate analysis has shown that comorbidities are significantly more associated with complicated appendicitis than sarcopenia. CONCLUSION: Geriatric patients with lower BMI, decreased muscle area, and CT‐detected sarcopenia have an increased risk of complicated appendicitis. Comorbidities are also important risk factors. Surgeons should be aware of factors leading to complicated appendicitis, which may cause higher morbidity and mortality rates in elderly patients.
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spelling pubmed-104988332023-09-14 The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients Yildirim, Ali Cihat Atlanoğlu, Şahinde Gedik, Mehmet Ali Zeren, Sezgin Ekici, Mehmet Fatih Aging Med (Milton) Original Articles OBJECTIVE: Geriatric patients have more complicated appendicitis, which leads to higher morbidity and mortality rates. Sarcopenia has been shown to have a negative impact on patients undergoing surgery. This study aims to reveal the predictive value of computerized tomography‐assessed (CT‐assessed) sarcopenia for complicated appendicitis in geriatric patients. METHODS: One‐hundred fifty‐four patients’ with acute appendicitis age, gender, co‐morbidities, appendicitis status, and body mass index (BMI) values were analyzed. The skeletal muscle index (SMI) and related measurements were evaluated. RESULTS: Fifty‐two percent of the patients had complicated, and 48% had uncomplicated appendicitis. There was a statistically significant difference between uncomplicated and complicated cases regarding BMI, SMI, and muscle area values (P < 0.05). The cutoff point by Receiver Operating Characteristic Curve analysis was conducted for SMI and showed 71% sensitivity and 52% specificity (P = 0.042). Multivariate analysis has shown that comorbidities are significantly more associated with complicated appendicitis than sarcopenia. CONCLUSION: Geriatric patients with lower BMI, decreased muscle area, and CT‐detected sarcopenia have an increased risk of complicated appendicitis. Comorbidities are also important risk factors. Surgeons should be aware of factors leading to complicated appendicitis, which may cause higher morbidity and mortality rates in elderly patients. John Wiley and Sons Inc. 2023-06-30 /pmc/articles/PMC10498833/ /pubmed/37711261 http://dx.doi.org/10.1002/agm2.12259 Text en © 2023 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Yildirim, Ali Cihat
Atlanoğlu, Şahinde
Gedik, Mehmet Ali
Zeren, Sezgin
Ekici, Mehmet Fatih
The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title_full The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title_fullStr The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title_full_unstemmed The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title_short The predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
title_sort predictive value of computerized tomography‐assessed sarcopenia for complicated appendicitis in geriatric patients
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498833/
https://www.ncbi.nlm.nih.gov/pubmed/37711261
http://dx.doi.org/10.1002/agm2.12259
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