Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

BACKGROUND: Using proteomics, we aimed to reveal molecular types of human atherosclerotic lesions and study their associations with histology, imaging, and cardiovascular outcomes. METHODS: Two hundred nineteen carotid endarterectomy samples were procured from 120 patients. A sequential protein extr...

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Detalles Bibliográficos
Autores principales: Theofilatos, Konstantinos, Stojkovic, Stefan, Hasman, Maria, van der Laan, Sander W., Baig, Ferheen, Barallobre-Barreiro, Javier, Schmidt, Lukas Emanuel, Yin, Siqi, Yin, Xiaoke, Burnap, Sean, Singh, Bhawana, Popham, Jude, Harkot, Olesya, Kampf, Stephanie, Nackenhorst, Maja Carina, Strassl, Andreas, Loewe, Christian, Demyanets, Svitlana, Neumayer, Christoph, Bilban, Martin, Hengstenberg, Christian, Huber, Kurt, Pasterkamp, Gerard, Wojta, Johann, Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10498884/
https://www.ncbi.nlm.nih.gov/pubmed/37646165
http://dx.doi.org/10.1161/CIRCRESAHA.123.322590

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