A Review of Recent Advances in Our Understanding of Neisseria gonorrhoeae

Gonorrhoea is an infection caused by bacteria that has recently been detected in humans and typically spreads through sexual contact. It leads to significant health issues in both prosperous and impoverished countries, culminating in significant yearly expenditures for diagnosis and treatment. Young adults who are involved in unprotected sexual activity and are promiscuous are particularly susceptible to gonorrhoea. It has been estimated that approximately 86.95 million individuals globally acquire the virus each year. Gonorrhoea has been reported to affect a variety of body parts, including the cervix in women and the urethra in males, as well as other areas such as the eyes, anus, throat, and, on rare occasions, the joints. It is momentarily the second most frequently reported sexually transmitted disease (STD) by the Centers for Disease Control and Prevention (CDC), trailing only chlamydia. Since the early 2000s, gonorrhoea cases have been on the rise globally, especially across many European nations, with an elevated prevalence among populations at higher risk of getting sexually transmitted infections (STIs), such as men who have sex with men and young heterosexual individuals. The fundamental objectives of gonorrhoea management techniques are to prevent, identify, and cure infections in patients and their partners in addition to minimizing the disease's stigma. It additionally involves monitoring antibiotic resistance and treatment failures, and it also involves advocating appropriate antimicrobial medication usage and stewardship.