Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3

Increased neurofilament light (NfL; NEFL) protein in biofluids is reflective of neurodegeneration and has gained interest as a biomarker across neurodegenerative diseases. In spinocerebellar ataxia type 3 (SCA3), the most common dominantly inherited ataxia, patients exhibit progressive NfL increases...

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Detalles Bibliográficos
Autores principales: Mengel, David, Wellik, Isabel G., Schuster, Kristen H., Jarrah, Sabrina I., Wacker, Madeleine, Ashraf, Naila S., Öz, Gülin, Synofzik, Matthis, Costa, Maria do Carmo, McLoughlin, Hayley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499033/
https://www.ncbi.nlm.nih.gov/pubmed/37664882
http://dx.doi.org/10.1242/dmm.050144

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