Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report

Type 4 hypersensitivity reactions convey a number of conditions that include fixed drug eruptions (FDEs). They share similar pathophysiologic backgrounds and sometimes presentation but can have very variable prognostications. Drugs are amongst the possible causes with acetaminophen and other NSAIDs...

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Autor principal: Alzahrani, Ali H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499053/
https://www.ncbi.nlm.nih.gov/pubmed/37711934
http://dx.doi.org/10.7759/cureus.43436
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author Alzahrani, Ali H
author_facet Alzahrani, Ali H
author_sort Alzahrani, Ali H
collection PubMed
description Type 4 hypersensitivity reactions convey a number of conditions that include fixed drug eruptions (FDEs). They share similar pathophysiologic backgrounds and sometimes presentation but can have very variable prognostications. Drugs are amongst the possible causes with acetaminophen and other NSAIDs being reported very frequently. We present a case of a patient reacting to flavoured oral ibuprofen and acetaminophen formulations, exhibiting FDEs with bullae formation. We describe our successful challenge to non-flavoured acetaminophen and ibuprofen. We briefly discuss FDEs in regard to their incidence, pathophysiology, and management.
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spelling pubmed-104990532023-09-14 Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report Alzahrani, Ali H Cureus Allergy/Immunology Type 4 hypersensitivity reactions convey a number of conditions that include fixed drug eruptions (FDEs). They share similar pathophysiologic backgrounds and sometimes presentation but can have very variable prognostications. Drugs are amongst the possible causes with acetaminophen and other NSAIDs being reported very frequently. We present a case of a patient reacting to flavoured oral ibuprofen and acetaminophen formulations, exhibiting FDEs with bullae formation. We describe our successful challenge to non-flavoured acetaminophen and ibuprofen. We briefly discuss FDEs in regard to their incidence, pathophysiology, and management. Cureus 2023-08-13 /pmc/articles/PMC10499053/ /pubmed/37711934 http://dx.doi.org/10.7759/cureus.43436 Text en Copyright © 2023, Alzahrani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Alzahrani, Ali H
Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title_full Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title_fullStr Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title_full_unstemmed Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title_short Fixed Drug Eruptions With Flavoured Liquid Formulations of Over-the-Counter Analgesics: A Case Report
title_sort fixed drug eruptions with flavoured liquid formulations of over-the-counter analgesics: a case report
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499053/
https://www.ncbi.nlm.nih.gov/pubmed/37711934
http://dx.doi.org/10.7759/cureus.43436
work_keys_str_mv AT alzahranialih fixeddrugeruptionswithflavouredliquidformulationsofoverthecounteranalgesicsacasereport

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