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Pre-existing CD4 T cell help boosts antibody responses but has limited impact on germinal center, antigen-specific B cell frequencies after influenza infection

The influenza virus is a persistent burden on global health, with seasonal vaccines providing incomplete protection. CD4(+) T cells help shape B cell and antibody responses; however, the selectivity of help and the effect on various antigen-specific B cell populations have not been fully elucidated....

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Detalles Bibliográficos
Autores principales: Besavilla, Danica F., Reusch, Laura, Enriquez, Josue, Schön, Karin, Angeletti, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499173/
https://www.ncbi.nlm.nih.gov/pubmed/37711622
http://dx.doi.org/10.3389/fimmu.2023.1243164