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Pre-existing CD4 T cell help boosts antibody responses but has limited impact on germinal center, antigen-specific B cell frequencies after influenza infection
The influenza virus is a persistent burden on global health, with seasonal vaccines providing incomplete protection. CD4(+) T cells help shape B cell and antibody responses; however, the selectivity of help and the effect on various antigen-specific B cell populations have not been fully elucidated....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499173/ https://www.ncbi.nlm.nih.gov/pubmed/37711622 http://dx.doi.org/10.3389/fimmu.2023.1243164 |