Cargando…

Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus

Dendritic spines, the tiny and actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain that control synaptic activity and plasticity. Dendritic spines contain a specialized form of endoplasmic reticulum (ER), i.e., the spine apparat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Hsiao-Tang, Lin, Yung-Jui, Wang, Ueh-Ting Tim, Lee, Sue-Ping, Liou, Yae-Huei, Chen, Bi-Chang, Hsueh, Yi-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499226/ https://www.ncbi.nlm.nih.gov/pubmed/37651441 http://dx.doi.org/10.1371/journal.pbio.3002274

Ejemplares similares

KLHL17/Actinfilin, a brain-specific gene associated with infantile spasms and autism, regulates dendritic spine enlargement
por: Hu, Hsiao-Tang, et al.
Publicado: (2020)

Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium
por: Bell, Miriam, et al.
Publicado: (2019)

Addendum: Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium
por: Bell, Miriam, et al.
Publicado: (2019)

Proximity proteomics of synaptopodin provides insight into the molecular composition of the spine apparatus of dendritic spines
por: Falahati, Hanieh, et al.
Publicado: (2022)

Calcium modeling of spine apparatus-containing human dendritic spines demonstrates an “all-or-nothing” communication switch between the spine head and dendrite
por: Rosado, James, et al.
Publicado: (2022)

Quantification of the density and morphology of dendritic spines and synaptic protein distribution using Thy1-YFP transgenic mice
por: Lin, Yung-Jui, et al.
Publicado: (2023)

Caldendrin and myosin V regulate synaptic spine apparatus localization via ER stabilization in dendritic spines
por: Konietzny, Anja, et al.
Publicado: (2021)

Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2
por: Sarowar, Tasnuva, et al.
Publicado: (2016)

VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation
por: Shih, Yu-Tzu, et al.
Publicado: (2016)

State-dependent diffusion of actin-depolymerizing factor/cofilin underlies the enlargement and shrinkage of dendritic spines
por: Noguchi, Jun, et al.
Publicado: (2016)

Recessive Mutations in SYNPO2 as a Candidate of Monogenic Nephrotic Syndrome
por: Mao, Youying, et al.
Publicado: (2020)

SYNPO2 upregulation is an unfavorable prognostic factor for nasopharyngeal carcinoma patients
por: Chang, Shih-Lun, et al.
Publicado: (2023)

From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation
por: Hsueh, Yi-Ping
Publicado: (2012)

The spine problem: finding a function for dendritic spines
por: Malanowski, Sarah, et al.
Publicado: (2014)

Molecular basis of interactions between CaMKII and α-actinin-2 that underlie dendritic spine enlargement
por: Curtis, Ashton J, et al.
Publicado: (2023)

Loss-of-Function Variants in the SYNPO2L Gene Are Associated With Atrial Fibrillation
por: Clausen, Alexander Guldmann, et al.
Publicado: (2021)

Ultrastructure of Dendritic Spines: Correlation Between Synaptic and Spine Morphologies
por: Arellano, Jon I., et al.
Publicado: (2007)

Spines slow dendrite diffusion
por: LeBrasseur, Nicole
Publicado: (2006)

Electrical Advantages of Dendritic Spines
por: Gulledge, Allan T., et al.
Publicado: (2012)

Dendritic Spine Plasticity and Cognition
por: González Burgos, Ignacio, et al.
Publicado: (2012)

Diffusion laws in dendritic spines
por: Holcman, David, et al.
Publicado: (2011)

Pathology of Synapses and Dendritic Spines
por: Knafo, Shira, et al.
Publicado: (2012)

Lipid dynamics at dendritic spines
por: Dotti, Carlos Gerardo, et al.
Publicado: (2014)

The discovery of dendritic spines by Cajal
por: Yuste, Rafael
Publicado: (2015)

Changing the size of dendritic spines
por: Saneyoshi, Takeo
Publicado: (2023)

The role of dendritic spines in epileptogenesis
por: Jean, Gary, et al.
Publicado: (2023)

Cytoskeleton Protein EB3 Contributes to Dendritic Spines Enlargement and Enhances Their Resilience to Toxic Effects of Beta-Amyloid
por: Pchitskaya, Ekaterina, et al.
Publicado: (2022)

Autism-linked mutations of CTTNBP2 reduce social interaction and impair dendritic spine formation via diverse mechanisms
por: Shih, Pu-Yun, et al.
Publicado: (2020)

SpineTool is an open-source software for analysis of morphology of dendritic spines
por: Ekaterina, Pchitskaya, et al.
Publicado: (2023)

Syndecan-2 induces filopodia and dendritic spine formation via the neurofibromin–PKA–Ena/VASP pathway
por: Lin, Yi-Ling, et al.
Publicado: (2007)

A model of activity-dependent changes in dendritic spine density and spine structure
por: Dur-e-Ahmad, Muhammad, et al.
Publicado: (2007)

Dendritic spine dynamics leading to spine elimination after repeated inductions of LTD
por: Hasegawa, Sho, et al.
Publicado: (2015)

Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory
por: Frank, Adam C., et al.
Publicado: (2018)

Activity-dependent trafficking of lysosomes in dendrites and dendritic spines
por: Goo, Marisa S., et al.
Publicado: (2017)

Dendritic spines cut loose to mature
por: Williams, Ruth
Publicado: (2007)

Cytoplasmic organization in cerebellar dendritic spines
Publicado: (1983)

Examining Form and Function of Dendritic Spines
por: Lee, Kevin F. H., et al.
Publicado: (2012)

Dendritic spine dysgenesis in Rett syndrome
por: Xu, Xin, et al.
Publicado: (2014)

Fine structure of synapses on dendritic spines
por: Frotscher, Michael, et al.
Publicado: (2014)

Levodopa treatment and dendritic spine pathology
por: Nishijima, Haruo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_v9as0ejf0th4f42a35sicrir7b