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Wounding the stroma: Docetaxel’s role in dormant breast cancer escape
The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499231/ https://www.ncbi.nlm.nih.gov/pubmed/37703292 http://dx.doi.org/10.1371/journal.pbio.3002297 |
| _version_ | 1785105663251185664 |
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| author | Cooper, Tyler T. Postovit, Lynne-Marie |
| author_facet | Cooper, Tyler T. Postovit, Lynne-Marie |
| author_sort | Cooper, Tyler T. |
| collection | PubMed |
| description | The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells. |
| format | Online Article Text |
| id | pubmed-10499231 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Public Library of Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-104992312023-09-14 Wounding the stroma: Docetaxel’s role in dormant breast cancer escape Cooper, Tyler T. Postovit, Lynne-Marie PLoS Biol Primer The mechanistic underpinnings of breast cancer recurrence following periods of dormancy are largely undetermined. A new study in PLOS Biology reveals that docetaxel-induced injury of tumour stromal cells stimulates the release of cytokines that support dormancy escape of breast cancer cells. Public Library of Science 2023-09-13 /pmc/articles/PMC10499231/ /pubmed/37703292 http://dx.doi.org/10.1371/journal.pbio.3002297 Text en © 2023 Cooper, Postovit https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| spellingShingle | Primer Cooper, Tyler T. Postovit, Lynne-Marie Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title | Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title_full | Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title_fullStr | Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title_full_unstemmed | Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title_short | Wounding the stroma: Docetaxel’s role in dormant breast cancer escape |
| title_sort | wounding the stroma: docetaxel’s role in dormant breast cancer escape |
| topic | Primer |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499231/ https://www.ncbi.nlm.nih.gov/pubmed/37703292 http://dx.doi.org/10.1371/journal.pbio.3002297 |
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