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β(2)ARs: double edge sword in heart function
Deng and colleagues highlight the importance of understanding the divergent roles of β2-adrenoceptor (β(2)AR) in high-fat diet-induced heart failure. β(2)AR signaling has beneficial and detrimental effects depending on the context and level of activation. We discuss the importance of these findings...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499308/ https://www.ncbi.nlm.nih.gov/pubmed/36990857 http://dx.doi.org/10.1016/j.molmed.2023.03.003 |
Sumario: | Deng and colleagues highlight the importance of understanding the divergent roles of β2-adrenoceptor (β(2)AR) in high-fat diet-induced heart failure. β(2)AR signaling has beneficial and detrimental effects depending on the context and level of activation. We discuss the importance of these findings and their implications in developing effective and safe therapies. |
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