Cargando…

The differing effects of a dual acting regulator on SIRT1

SIRT1 is an NAD(+)-dependent protein deacetylase that has been shown to play a significant role in many biological pathways, such as insulin secretion, tumor formation, lipid metabolism, and neurodegeneration. There is great interest in understanding the regulation of SIRT1 to better understand SIRT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hur, Yujin, Huynh, Johnson, Leong, Emily, Dosanjh, Reena, Charvat, Annemarie F., Vu, My H., Alam, Zain, Lee, Yue Tong, Cabreros, Christiane C., Carroll, Emma C., Hura, Greg L., Wang, Ningkun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499324/ https://www.ncbi.nlm.nih.gov/pubmed/37711385 http://dx.doi.org/10.3389/fmolb.2023.1260489

Ejemplares similares

Nitric oxide-based regulation of metabolism: Hints from TRAP1 and SIRT3 crosstalk
por: Faienza, Fiorella, et al.
Publicado: (2022)

A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia
por: Rodden, Layne N., et al.
Publicado: (2022)

P23 Acts as Functional RBP in the Macrophage Inflammation Response
por: de Vries, Sebastian, et al.
Publicado: (2021)

SYDE1 Acts as an Oncogene in Glioma and has Diagnostic and Prognostic Values
por: Han, Zhenyuan, et al.
Publicado: (2021)

Hemoglobin can Act as a (Pseudo)-Peroxidase in Vivo. What is the Evidence?
por: Alayash, Abdu I., et al.
Publicado: (2022)

LRMP Associates With Immune Infiltrates and Acts as a Prognostic Biomarker in Lung Adenocarcinoma
por: Jin, Xin, et al.
Publicado: (2021)

Structure, Function and Protein Engineering of Cereal-Type Inhibitors Acting on Amylolytic Enzymes
por: Møller, Marie Sofie, et al.
Publicado: (2022)

VASH-1 Regulates Oxidative Stress and Fibrosis in Diabetic Kidney Disease via SIRT1/HIF1α and TGFβ1/Smad3 Signaling Pathways
por: Ren, Huiwen, et al.
Publicado: (2020)

Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients
por: Tripathi, Gaurav, et al.
Publicado: (2022)

Plasmid parB contributes to uropathogenic Escherichia coli colonization in vivo by acting on biofilm formation and global gene regulation
por: Song, Ningning, et al.
Publicado: (2022)

Sense and antisense RNA products of the uxuR gene can affect motility and chemotaxis acting independent of the UxuR protein
por: Tutukina, Maria N., et al.
Publicado: (2023)

Long Non-Coding RNA AP000695.2 Acts as a Novel Prognostic Biomarker and Regulates the Cell Growth and Migration of Lung Adenocarcinoma
por: Wang, Chunyan, et al.
Publicado: (2022)

Genetic and Functional Analyses of Archaeal ATP-Dependent RNA Ligase in C/D Box sRNA Circularization and Ribosomal RNA Processing
por: Liu, Yancheng, et al.
Publicado: (2022)

Endogenous PTEN acts as the key determinant for mTOR inhibitor sensitivity by inducing the stress-sensitized PTEN-mediated death axis in KSHV-associated malignant cells
por: Das, Piyanki, et al.
Publicado: (2023)

High-Intensity Aerobic Exercise Suppresses Cancer Growth by Regulating Skeletal Muscle-Derived Oncogenes and Tumor Suppressors
por: Jee, Hyunseok, et al.
Publicado: (2022)

LyeTxI-b, a Synthetic Peptide Derived From a Spider Venom, Is Highly Active in Triple-Negative Breast Cancer Cells and Acts Synergistically With Cisplatin
por: de Avelar Júnior, Joaquim Teixeira, et al.
Publicado: (2022)

Differential Wound Healing Capacity of Mesenchymal Stem Cell-Derived Exosomes Originated From Bone Marrow, Adipose Tissue and Umbilical Cord Under Serum- and Xeno-Free Condition
por: Hoang, Diem Huong, et al.
Publicado: (2020)

Changes in antioxidant status and DNA repair capacity are corroborated with molecular alterations in malignant thyroid tissue of patients with papillary thyroid cancer
por: Eng, Zing Hong, et al.
Publicado: (2023)

Assessing the epithelial-to-mesenchymal plasticity in a small cell lung carcinoma (SCLC) and lung fibroblasts co-culture model
por: Dhungel, Nilu, et al.
Publicado: (2023)

Biodegradable manganese-doped hydroxyapatite antitumor adjuvant as a promising photo-therapeutic for cancer treatment
por: Park, Sumin, et al.
Publicado: (2022)

Profiling Urinary Sulfate Metabolites With Mass Spectrometry
por: Fitzgerald, Christopher C. J., et al.
Publicado: (2022)

Sphingosine Kinase 1 Signaling in Breast Cancer: A Potential Target to Tackle Breast Cancer Stem Cells
por: Hii, Ling-Wei, et al.
Publicado: (2021)

Structural investigation of human cystine/glutamate antiporter system x(c) (−) (Sx(c) (−)) using homology modeling and molecular dynamics
por: Hang, Tran Dieu, et al.
Publicado: (2022)

The Role of ClpB in Bacterial Stress Responses and Virulence
por: Alam, Athar, et al.
Publicado: (2021)

Metformin Induces PRODH/POX-Dependent Apoptosis in Breast Cancer Cells
por: Huynh, Thi Yen Ly, et al.
Publicado: (2022)

Gene expression profile analysis to discover molecular signatures for early diagnosis and therapies of triple-negative breast cancer
por: Alam, Md Shahin, et al.
Publicado: (2022)

Bioinformatic Analyses of Canonical Pathways of TSPOAP1 and its Roles in Human Diseases
por: Suthar, Sharad Kumar, et al.
Publicado: (2021)

Inactivation of Cerebral Cavernous Malformation Genes Results in Accumulation of von Willebrand Factor and Redistribution of Weibel-Palade Bodies in Endothelial Cells
por: Much, Christiane D., et al.
Publicado: (2021)

MicroRNA Expression and Intestinal Permeability in Children Living in a Slum Area of Bangladesh
por: Rashid, Humaira, et al.
Publicado: (2021)

Porcine blood cell and brain tissue energy metabolism: Effects of “early life stress”
por: Münz, Franziska, et al.
Publicado: (2023)

Mycobacterium tuberculosis Methyltransferase Rv1515c Can Suppress Host Defense Mechanisms by Modulating Immune Functions Utilizing a Multipronged Mechanism
por: Rani, Anshu, et al.
Publicado: (2022)

Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome
por: Amir, Mohd., et al.
Publicado: (2019)

ERK signaling for cell migration and invasion
por: Samson, Shiela C., et al.
Publicado: (2022)

Multiplex Immunofluorescence and Multispectral Imaging: Forming the Basis of a Clinical Test Platform for Immuno-Oncology
por: Hoyt, Clifford C.
Publicado: (2021)

First Principles Calculation of Protein–Protein Dimer Affinities of ALS-Associated SOD1 Mutants
por: Hsueh, Shawn C. C., et al.
Publicado: (2022)

Hippo Signaling-Mediated Mechanotransduction in Cell Movement and Cancer Metastasis
por: Chang, Yu-Chiuan, et al.
Publicado: (2020)

Using Small-Angle Scattering Data and Parametric Machine Learning to Optimize Force Field Parameters for Intrinsically Disordered Proteins
por: Demerdash, Omar, et al.
Publicado: (2019)

Application of feature-based molecular networking and MassQL for the MS/MS fragmentation study of depsipeptides
por: Selegato, Denise M., et al.
Publicado: (2023)

Editorial: Molecular Diagnostics in the Detection of Neurodegenerative Disorders
por: Agrawal, Megha, et al.
Publicado: (2017)

Nucleosome Remodeling by Fun30(SMARCAD1) in the DNA Damage Response
por: Bantele, Susanne C. S., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5876upd5i6cnrk743ponqghu05