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Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis

Difelikefalin is a selective kappa opioid receptor agonist approved for treating moderate‐to‐severe pruritus in adults undergoing hemodialysis (HD). Difelikefalin is not a controlled substance under the Controlled Substances Act. This study assessed the potential for developing physical dependence o...

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Detalles Bibliográficos
Autores principales: Spencer, Robert H., Munera, Catherine, Shram, Megan J., Menzaghi, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499405/
https://www.ncbi.nlm.nih.gov/pubmed/37128642
http://dx.doi.org/10.1111/cts.13538