Discovery and validation of PURA as a transcription target of 20(S)-protopanaxadiol: Implications for the treatment of cognitive dysfunction

BACKGROUND: 20(S)-protopanaxadiol (PPD), a ginsenoside metabolite, has prominent benefits for the central nervous system, especially in improving learning and memory. However, its transcriptional targets in brain tissue remain unknown. METHODS: In this study, we first used mass spectrometry-based dr...

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Detalles Bibliográficos
Autores principales: Chen, Feiyan, Zhang, Wenjing, Xu, Shuyi, Zhang, Hantao, Chen, Lin, Chen, Cuihua, Zhu, Zhu, Zhao, Yunan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499581/
https://www.ncbi.nlm.nih.gov/pubmed/37720572
http://dx.doi.org/10.1016/j.jgr.2023.04.007

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