Cargando…

Gut microbial carbohydrate metabolism contributes to insulin resistance

Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2 diabetes(1,2). Previous metagenomic studies have described the characteristics of gut microbiota and their roles in metabolizing major nutrients in insulin resistance(3–9). In particular, carbohydrate metaboli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takeuchi, Tadashi, Kubota, Tetsuya, Nakanishi, Yumiko, Tsugawa, Hiroshi, Suda, Wataru, Kwon, Andrew Tae-Jun, Yazaki, Junshi, Ikeda, Kazutaka, Nemoto, Shino, Mochizuki, Yoshiki, Kitami, Toshimori, Yugi, Katsuyuki, Mizuno, Yoshiko, Yamamichi, Nobutake, Yamazaki, Tsutomu, Takamoto, Iseki, Kubota, Naoto, Kadowaki, Takashi, Arner, Erik, Carninci, Piero, Ohara, Osamu, Arita, Makoto, Hattori, Masahira, Koyasu, Shigeo, Ohno, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499599/ https://www.ncbi.nlm.nih.gov/pubmed/37648852 http://dx.doi.org/10.1038/s41586-023-06466-x

Ejemplares similares

Elucidation of Gut Microbiota-Associated Lipids Using LC-MS/MS and 16S rRNA Sequence Analyses
por: Yasuda, Shu, et al.
Publicado: (2020)

Role of insulin receptor substrates in the progression of hepatocellular carcinoma
por: Sakurai, Yoshitaka, et al.
Publicado: (2017)

Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains
por: Nemoto, Shino, et al.
Publicado: (2022)

Exploring body weight-influencing gut microbiota by elucidating the association with diet and host gene expression
por: Nemoto, Shino, et al.
Publicado: (2023)

Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity
por: Kubota, Tetsuya, et al.
Publicado: (2018)

Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library
por: Tsugawa, Hiroshi, et al.
Publicado: (2017)

Characterization of Lipid Profiles after Dietary Intake of Polyunsaturated Fatty Acids Using Integrated Untargeted and Targeted Lipidomics
por: Naoe, Satoko, et al.
Publicado: (2019)

Niclosamide activates the NLRP3 inflammasome by intracellular acidification and mitochondrial inhibition
por: Thi Tran, Uyen, et al.
Publicado: (2019)

Pioglitazone Ameliorates Smooth Muscle Cell Proliferation in Cuff-Induced Neointimal Formation by Both Adiponectin-Dependent and -Independent Pathways
por: Kubota, Tetsuya, et al.
Publicado: (2016)

In Situ Reconstruction with Extended Debridement in Patients with Mycotic Abdominal Aortic Aneurysms
por: Nemoto, Youkou, et al.
Publicado: (2017)

The selective control of glycolysis, gluconeogenesis and glycogenesis by temporal insulin patterns
por: Noguchi, Rei, et al.
Publicado: (2013)

The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression
por: Akimoto, Yuki, et al.
Publicado: (2013)

Stage-Specific De Novo Synthesis of Very-Long-Chain Dihydroceramides Confers Dormancy to Entamoeba Parasites
por: Mi-ichi, Fumika, et al.
Publicado: (2021)

Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood
por: Aihara, Masakazu, et al.
Publicado: (2020)

Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity
por: Kubota, Naoto, et al.
Publicado: (2016)

Computational mass spectrometry accelerates C = C position-resolved untargeted lipidomics using oxygen attachment dissociation
por: Uchino, Haruki, et al.
Publicado: (2022)

Mass Spectrometry Data Repository Enhances Novel Metabolite Discoveries with Advances in Computational Metabolomics
por: Tsugawa, Hiroshi, et al.
Publicado: (2019)

Pleiotropic Roles of Cholesteryl Sulfate during Entamoeba Encystation: Involvement in Cell Rounding and Development of Membrane Impermeability
por: Mi-ichi, Fumika, et al.
Publicado: (2022)

Unique features of Entamoeba histolytica glycerophospholipid metabolism; has the E. histolytica lipid metabolism network evolved through gene loss and gain to enable parasitic life cycle adaptation?
por: Mi-ichi, Fumika, et al.
Publicado: (2023)

GC/MS based metabolomics: development of a data mining system for metabolite identification by using soft independent modeling of class analogy (SIMCA)
por: Tsugawa, Hiroshi, et al.
Publicado: (2011)

Global profiling of gut microbiota-associated lipid metabolites in antibiotic-treated mice by LC-MS/MS-based analyses
por: Okahashi, Nobuyuki, et al.
Publicado: (2021)

MS-DIAL: Data Independent MS/MS Deconvolution for Comprehensive Metabolome Analysis
por: Tsugawa, Hiroshi, et al.
Publicado: (2015)

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice
por: Furuzono, Shinji, et al.
Publicado: (2021)

The Role of DJ-1 in Cellular Metabolism and Pathophysiological Implications for Parkinson’s Disease
por: Mencke, Pauline, et al.
Publicado: (2021)

A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice
por: Kobayashi, Ami, et al.
Publicado: (2023)

Hybrid dynamic/static method for large-scale simulation of metabolism
por: Yugi, Katsuyuki, et al.
Publicado: (2005)

Role of Innate Lymphocytes in Infection and Inflammation
por: Koyasu, Shigeo, et al.
Publicado: (2012)

Innate lymphoid cells, possible interaction with microbiota
por: Moro, Kazuyo, et al.
Publicado: (2014)

Innate Lymphoid Cells in Skin Homeostasis and Malignancy
por: Wagner, Marek, et al.
Publicado: (2021)

Seasonal variation of serum KL-6 concentrations is greater in patients with hypersensitivity pneumonitis
por: Ohnishi, Hiroshi, et al.
Publicado: (2014)

Deep sternal wound infection after cardiac surgery
por: Kubota, Hiroshi, et al.
Publicado: (2013)

Application of a SYBR® Green One Step Real-time RT-PCR Assay to Detect Type 1 Porcine Reproductive and Respiratory Syndrome Virus
por: ISEKI, Hiroshi, et al.
Publicado: (2014)

Pathogenicity of emerging Japanese type 1 porcine reproductive and respiratory syndrome virus in experimentally infected pigs
por: ISEKI, Hiroshi, et al.
Publicado: (2015)

A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
por: Yugi, Katsuyuki, et al.
Publicado: (2005)

Multiple Omics Uncovers Host–Gut Microbial Mutualism During Prebiotic Fructooligosaccharide Supplementation
por: Kato, Tamotsu, et al.
Publicado: (2014)

Effect of Metabolically Healthy Obesity on the Development of Carotid Plaque in the General Population: A Community-Based Cohort Study
por: Itoh, Hidetaka, et al.
Publicado: (2020)

ILC2s and Adipose Tissue Homeostasis: Progress to Date and the Road Ahead
por: Misawa, Takuma, et al.
Publicado: (2022)

Ambulance Transport of Patients with Mild Conditions in Hokkaido, Japan
por: Yazaki, Hiroshi, et al.
Publicado: (2020)

A proliferative probiotic Bifidobacterium strain in the gut ameliorates progression of metabolic disorders via microbiota modulation and acetate elevation
por: Aoki, Ryo, et al.
Publicado: (2017)

Asymptomatic left atrial appendage aneurysm (LAAA) with pericardial defect in a 1-year-old girl
por: Ota, Chiharu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8f4srdmsvdh1uotcisk11l4o4k