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Inferring and perturbing cell fate regulomes in human brain organoids

Self-organizing neural organoids grown from pluripotent stem cells(1–3) combined with single-cell genomic technologies provide opportunities to examine gene regulatory networks underlying human brain development. Here we acquire single-cell transcriptome and accessible chromatin data over a dense ti...

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Detalles Bibliográficos
Autores principales:	Fleck, Jonas Simon, Jansen, Sophie Martina Johanna, Wollny, Damian, Zenk, Fides, Seimiya, Makiko, Jain, Akanksha, Okamoto, Ryoko, Santel, Malgorzata, He, Zhisong, Camp, J. Gray, Treutlein, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499607/ https://www.ncbi.nlm.nih.gov/pubmed/36198796 http://dx.doi.org/10.1038/s41586-022-05279-8

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