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Ultrastructural features mirror metabolic derangement in human endothelial cells exposed to high glucose

High glucose-induced endothelial dysfunction is the early event that initiates diabetes-induced vascular disease. Here we employed Cryo Soft X-ray Tomography to obtain three-dimensional maps of high d-glucose-treated endothelial cells and their controls at nanometric spatial resolution. We then corr...

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Detalles Bibliográficos
Autores principales:	Scrimieri, Roberta, Locatelli, Laura, Cazzaniga, Alessandra, Cazzola, Roberta, Malucelli, Emil, Sorrentino, Andrea, Iotti, Stefano, Maier, Jeanette A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499809/ https://www.ncbi.nlm.nih.gov/pubmed/37704683 http://dx.doi.org/10.1038/s41598-023-42333-5

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