Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

The virus life cycle depends on host-virus protein-protein interactions, which often involve a disordered protein region binding to a folded protein domain. Here, we used proteomic peptide phage display (ProP-PD) to identify peptides from the intrinsically disordered regions of the human proteome th...

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Detalles Bibliográficos
Autores principales: Mihalič, Filip, Benz, Caroline, Kassa, Eszter, Lindqvist, Richard, Simonetti, Leandro, Inturi, Raviteja, Aronsson, Hanna, Andersson, Eva, Chi, Celestine N., Davey, Norman E., Överby, Anna K., Jemth, Per, Ivarsson, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499821/
https://www.ncbi.nlm.nih.gov/pubmed/37704626
http://dx.doi.org/10.1038/s41467-023-41312-8

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