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Prebiotic inulin enhances gut microbial metabolism and anti-inflammation in apolipoprotein E4 mice with sex-specific implications

Gut dysbiosis has been identified as a crucial factor of Alzheimer's disease (AD) development for apolipoprotein E4 (APOE4) carriers. Inulin has shown the potential to mitigate dysbiosis. However, it remains unclear whether the dietary response varies depending on sex. In the study, we fed 4-mo...

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Detalles Bibliográficos
Autores principales: Chang, Ya-Hsuan, Yanckello, Lucille M., Chlipala, George E., Green, Stefan J., Aware, Chetan, Runge, Amelia, Xing, Xin, Chen, Anna, Wenger, Kathryn, Flemister, Abeoseh, Wan, Caixia, Lin, Ai-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499887/
https://www.ncbi.nlm.nih.gov/pubmed/37704738
http://dx.doi.org/10.1038/s41598-023-42381-x