Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical need to identify, target and manipulate specific cell populations expressing the mu-opioid receptor (MOR). However, available tools and transgenic models for gaining long-term genetic access to MOR+ neural...

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Detalles Bibliográficos
Autores principales: Salimando, Gregory J., Tremblay, Sébastien, Kimmey, Blake A., Li, Jia, Rogers, Sophie A., Wojick, Jessica A., McCall, Nora M., Wooldridge, Lisa M., Rodrigues, Amrith, Borner, Tito, Gardiner, Kristin L., Jayakar, Selwyn S., Singeç, Ilyas, Woolf, Clifford J., Hayes, Matthew R., De Jonghe, Bart C., Bennett, F. Christian, Bennett, Mariko L., Blendy, Julie A., Platt, Michael L., Creasy, Kate Townsend, Renthal, William R., Ramakrishnan, Charu, Deisseroth, Karl, Corder, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499891/
https://www.ncbi.nlm.nih.gov/pubmed/37704594
http://dx.doi.org/10.1038/s41467-023-41407-2

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