Cargando…

Spatial immune profiling of glioblastoma identifies an inflammatory, perivascular phenotype associated with longer survival

Detalles Bibliográficos
Autores principales:	Wirsching, Hans-Georg, Felsberg, Jörg, Prummer, Michael, Moisoiu, Vlad, Lourman, Roxanne, Hertler, Caroline, Antonios, Michelle, Cimino, Patrick J., Roth, Patrick, Gorlia, Thierry, Prins, Robert M., Cloughesy, Timothy, Wen, Patrick Y., Holland, Eric C., Reifenberger, Guido, Weller, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Correspondence
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499942/ https://www.ncbi.nlm.nih.gov/pubmed/37573572 http://dx.doi.org/10.1007/s00401-023-02617-6

Ejemplares similares

Computational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma
por: Randles, Amanda, et al.
Publicado: (2021)

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery
por: Cimino, Patrick J., et al.
Publicado: (2017)

Associations of levetiracetam use with the safety and tolerability profile of chemoradiotherapy for patients with newly diagnosed glioblastoma
por: Seystahl, Katharina, et al.
Publicado: (2022)

Targeted Therapies and Immune Checkpoint Inhibitors in Primary CNS Lymphoma
por: Wirsching, Hans-Georg, et al.
Publicado: (2021)

Interferon-β exposure induces a fragile glioblastoma stem cell phenotype with a transcriptional profile of reduced migratory and MAPK pathway activity
por: Lohmann, Birthe, et al.
Publicado: (2020)

Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells
por: Wolpert, Fabian, et al.
Publicado: (2015)

Chemotherapy for intracranial ependymoma in adults
por: Gramatzki, Dorothee, et al.
Publicado: (2016)

How we treat glioblastoma
por: Weller, Michael, et al.
Publicado: (2019)

Radiotherapy for glioblastoma patients with poor performance status
por: Schröder, Christina, et al.
Publicado: (2021)

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery
por: Stummer, Walter, et al.
Publicado: (2012)

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome
por: Weller, Michael, et al.
Publicado: (2016)

Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma
por: Molina, Maria L., et al.
Publicado: (2019)

MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM
por: Stojcheva, Nina, et al.
Publicado: (2016)

Radiomic Analysis to Predict Outcome in Recurrent Glioblastoma Based on Multi-Center MR Imaging From the Prospective DIRECTOR Trial
por: Vils, Alex, et al.
Publicado: (2021)

Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials
por: Ellingson, Benjamin M., et al.
Publicado: (2017)

MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape
por: Codo, Paula, et al.
Publicado: (2014)

Control of glioma cell migration and invasiveness by GDF-15
por: Codó, Paula, et al.
Publicado: (2016)

Venous thromboembolic events in glioblastoma patients: An epidemiological study
por: Eisele, Amanda, et al.
Publicado: (2022)

Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma
por: Cimino, Patrick J., et al.
Publicado: (2018)

Glioblastoma and Increased Survival with Longer Chemotherapy Duration
por: Jaoude, Dory Abou, et al.
Publicado: (2019)

Radiogenomic modeling predicts survival-associated prognostic groups in glioblastoma
por: Nuechterlein, Nicholas, et al.
Publicado: (2021)

The pathological structure of the perivascular niche in different microvascular patterns of glioblastoma
por: Chen, Jintao, et al.
Publicado: (2017)

Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells
por: Burgett, Monica E., et al.
Publicado: (2016)

Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model
por: Ngo, Mai T., et al.
Publicado: (2022)

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype
por: Wu, Yonghe, et al.
Publicado: (2020)

Droplet digital PCR-based analyses for robust, rapid, and sensitive molecular diagnostics of gliomas
por: Wolter, Marietta, et al.
Publicado: (2022)

Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition
por: Silginer, Manuela, et al.
Publicado: (2023)

On the origin and development of glioblastoma: multifaceted role of perivascular mesenchymal stromal cells
por: Ah-Pine, F., et al.
Publicado: (2023)

Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide
por: Berger, Kerstin, et al.
Publicado: (2020)

Negative allosteric modulators of metabotropic glutamate receptor 3 target the stem-like phenotype of glioblastoma
por: Wirsching, Hans-Georg, et al.
Publicado: (2020)

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy
por: Cloughesy, Timothy F, et al.
Publicado: (2018)

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy
por: Wen, Patrick Y, et al.
Publicado: (2018)

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele
por: Hawkes, Cheryl A., et al.
Publicado: (2012)

Re-irradiation of recurrent IDH-wildtype glioblastoma in the bevacizumab and immunotherapy era: Target delineation, outcomes and patterns of recurrence
por: Christ, Sebastian M., et al.
Publicado: (2023)

The molecular landscape of adult diffuse gliomas and relevance to clinical trials
por: Cimino, Patrick J., et al.
Publicado: (2019)

Chimeric antigen receptors in the brain: Can we tackle glioblastoma with engineered NK cells?
por: Roth, Patrick
Publicado: (2023)

EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells
por: Krusche, Benjamin, et al.
Publicado: (2016)

Biological activity of tumor-treating fields in preclinical glioma models
por: Silginer, Manuela, et al.
Publicado: (2017)

Programmed death ligand 1 gene silencing in murine glioma models reveals cell line-specific modulation of tumor growth in vivo
por: Blomberg, Evelina, et al.
Publicado: (2022)

Differential roles of type I interferon signaling in tumor versus host cells in experimental glioma models()
por: Blomberg, Evelina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t4eqtd5s44il5jksholhh111sb