RB loss sensitizes cells to replication-associated DNA damage after PARP inhibition by trapping

The retinoblastoma tumor suppressor protein (RB) interacts physically and functionally with a number of epigenetic modifying enzymes to control transcriptional regulation, respond to replication stress, promote DNA damage response and repair, and regulate genome stability. To better understand how d...

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Detalles Bibliográficos
Autores principales: Zamalloa, Luis Gregory, Pruitt, Margaret M, Hermance, Nicole M, Gali, Himabindu, Flynn, Rachel L, Manning, Amity L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500056/
https://www.ncbi.nlm.nih.gov/pubmed/37704395
http://dx.doi.org/10.26508/lsa.202302067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500056/
https://www.ncbi.nlm.nih.gov/pubmed/37704395
http://dx.doi.org/10.26508/lsa.202302067

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