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Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand

INTRODUCTION: Patients with head and neck cancer (HNC) are particularly susceptible to dysphagia and malnutrition. Prophylactic percutaneous endoscopic gastrostomy (PEG) placement is a method used to manage these issues, but practices vary among institutions. At Midcentral District Health Board, pat...

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Autores principales: Fong, Su Chen, Pandey, Ramesh, Rajaretnam, Michelle, Delaibatiki, Miriama, Peel, David N.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500120/
https://www.ncbi.nlm.nih.gov/pubmed/37403761
http://dx.doi.org/10.1002/jmrs.699
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author Fong, Su Chen
Pandey, Ramesh
Rajaretnam, Michelle
Delaibatiki, Miriama
Peel, David N.Y.
author_facet Fong, Su Chen
Pandey, Ramesh
Rajaretnam, Michelle
Delaibatiki, Miriama
Peel, David N.Y.
author_sort Fong, Su Chen
collection PubMed
description INTRODUCTION: Patients with head and neck cancer (HNC) are particularly susceptible to dysphagia and malnutrition. Prophylactic percutaneous endoscopic gastrostomy (PEG) placement is a method used to manage these issues, but practices vary among institutions. At Midcentral District Health Board, patients receiving radiotherapy to the primary and bilateral neck regions routinely undergo prophylactic PEG placement. This study aimed to review the nutritional and PEG‐related outcomes of these patients. METHODS: Records of 49 patients were retrospectively reviewed. Their demographics, tumour and treatment characteristics were recorded. We evaluated patient weight loss, non‐elective hospitalisation, treatment interruption rates, PEG‐related complications, usage, dependency rates and late dysphagia rates. RESULTS: Oropharyngeal cancers were the most common primary site (61.2%), and 83.7% of patients received primary chemoradiotherapy. Mean weight loss at treatment completion was 5.6% ± 4.3 (4.6 kg ± 3.9). The rate of non‐elective hospitalisations was 26.5%, and only 2% of patients had treatment interruptions. Peristomal infection was the most frequent PEG complication (20.4%). No PEG‐related mortality was reported. Median duration of PEG dependency was 97 days (14–388 days). Two patients remained permanently dependent at 3 years due to grade 3 dysphagia, and six patients experienced grade ≥2 late dysphagia. CONCLUSION: Our study showed that prophylactic PEG tube placement was relatively safe, with a high utilisation rate and low long‐term dependence on PEG tubes after treatment completion. However, complications related to their use should be addressed through a multidisciplinary approach, with careful assessment by clinicians. The weight loss and hospitalisation rates observed were consistent with earlier studies that utilised prophylactic PEG tubes.
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spelling pubmed-105001202023-09-15 Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand Fong, Su Chen Pandey, Ramesh Rajaretnam, Michelle Delaibatiki, Miriama Peel, David N.Y. J Med Radiat Sci Original Articles INTRODUCTION: Patients with head and neck cancer (HNC) are particularly susceptible to dysphagia and malnutrition. Prophylactic percutaneous endoscopic gastrostomy (PEG) placement is a method used to manage these issues, but practices vary among institutions. At Midcentral District Health Board, patients receiving radiotherapy to the primary and bilateral neck regions routinely undergo prophylactic PEG placement. This study aimed to review the nutritional and PEG‐related outcomes of these patients. METHODS: Records of 49 patients were retrospectively reviewed. Their demographics, tumour and treatment characteristics were recorded. We evaluated patient weight loss, non‐elective hospitalisation, treatment interruption rates, PEG‐related complications, usage, dependency rates and late dysphagia rates. RESULTS: Oropharyngeal cancers were the most common primary site (61.2%), and 83.7% of patients received primary chemoradiotherapy. Mean weight loss at treatment completion was 5.6% ± 4.3 (4.6 kg ± 3.9). The rate of non‐elective hospitalisations was 26.5%, and only 2% of patients had treatment interruptions. Peristomal infection was the most frequent PEG complication (20.4%). No PEG‐related mortality was reported. Median duration of PEG dependency was 97 days (14–388 days). Two patients remained permanently dependent at 3 years due to grade 3 dysphagia, and six patients experienced grade ≥2 late dysphagia. CONCLUSION: Our study showed that prophylactic PEG tube placement was relatively safe, with a high utilisation rate and low long‐term dependence on PEG tubes after treatment completion. However, complications related to their use should be addressed through a multidisciplinary approach, with careful assessment by clinicians. The weight loss and hospitalisation rates observed were consistent with earlier studies that utilised prophylactic PEG tubes. John Wiley and Sons Inc. 2023-07-05 2023-09 /pmc/articles/PMC10500120/ /pubmed/37403761 http://dx.doi.org/10.1002/jmrs.699 Text en © 2023 The Authors. Journal of Medical Radiation Sciences published by John Wiley & Sons Australia, Ltd on behalf of Australian Society of Medical Imaging and Radiation Therapy and New Zealand Institute of Medical Radiation Technology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Fong, Su Chen
Pandey, Ramesh
Rajaretnam, Michelle
Delaibatiki, Miriama
Peel, David N.Y.
Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title_full Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title_fullStr Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title_full_unstemmed Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title_short Routine Prophylactic Percutaneous Endoscopic Gastrostomy in Head and Neck Cancers with Bilateral Neck Irradiation: A Regional Cancer Experience in New Zealand
title_sort routine prophylactic percutaneous endoscopic gastrostomy in head and neck cancers with bilateral neck irradiation: a regional cancer experience in new zealand
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500120/
https://www.ncbi.nlm.nih.gov/pubmed/37403761
http://dx.doi.org/10.1002/jmrs.699
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