IL-6 trans-signaling in a humanized mouse model of scleroderma

Fibrosis is regulated by interactions between immune and mesenchymal cells. However, the capacity of cell types to modulate human fibrosis pathology is poorly understood due to lack of a fully humanized model system. MISTRG6 mice were engineered by homologous mouse/human gene replacement to develop...

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Detalles Bibliográficos
Autores principales: Odell, Ian D., Agrawal, Kriti, Sefik, Esen, Odell, Anahi V., Caves, Elizabeth, Kirkiles-Smith, Nancy C., Horsley, Valerie, Hinchcliff, Monique, Pober, Jordan S., Kluger, Yuval, Flavell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500188/
https://www.ncbi.nlm.nih.gov/pubmed/37669366
http://dx.doi.org/10.1073/pnas.2306965120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500188/
https://www.ncbi.nlm.nih.gov/pubmed/37669366
http://dx.doi.org/10.1073/pnas.2306965120

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