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Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance

Antimicrobial resistance (AMR) is a major global problem and threat to humanity. The search for new antibiotics is directed towards targeting of novel microbial systems and enzymes, as well as augmenting the activity of pre-existing antimicrobials. Sulphur-containing metabolites (e.g., auranofin and...

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Detalles Bibliográficos
Autores principales: Downes, Shane G., Doyle, Sean, Jones, Gary W., Owens, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500201/
https://www.ncbi.nlm.nih.gov/pubmed/36876884
http://dx.doi.org/10.1042/EBC20220222

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