Design, synthesis, molecular docking and DFT studies on novel melatonin and isatin based azole derivatives

In order to address the pressing demand for newer broad-spectrum antifungal medicines with enhanced activity, computer modelling was utilised to rationally develop newer antifungal azole-based drugs. Based on the drug and active sites of the Lanosterol 14 alpha-Demethylases (LAD) of the prominent fu...

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Detalles Bibliográficos
Autores principales: Saini, Keshav Kumar, Upadhyay, Ravindra Kumar, Kant, Ravi, Vajpayee, Arpita, Jain, Kalpana, Kumar, Amit, Kumar, Lalita S., Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500251/
https://www.ncbi.nlm.nih.gov/pubmed/37720826
http://dx.doi.org/10.1039/d3ra05531k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500251/
https://www.ncbi.nlm.nih.gov/pubmed/37720826
http://dx.doi.org/10.1039/d3ra05531k

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