Kallistatin Deficiency Induces the Oxidative Stress-Related Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells: A Novel Protagonist in Age-Related Macular Degeneration

PURPOSE: Retinal pigment epithelium (RPE) dysfunction induced by oxidative stress–related epithelial-mesenchymal transition (EMT) of RPE is the primary underlying mechanism of age-related macular degeneration (AMD). Kallistatin (KAL) is a secreted protein with an antioxidative stress effect. However...

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Detalles Bibliográficos
Autores principales: Shen, Gang, Li, Yanmei, Zeng, Yongcheng, Hong, Fuyan, Zhang, Jing, Wang, Yan, Zhang, Chengwei, Xiang, Wei, Wang, Jinhong, Fang, Zhenzhen, Qi, Weiwei, Yang, Xia, Gao, Guoquan, Zhou, Ti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500364/
https://www.ncbi.nlm.nih.gov/pubmed/37682567
http://dx.doi.org/10.1167/iovs.64.12.15

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