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Chemically augmented malaria sporozoites display an altered immunogenic profile

Despite promising results in malaria-naïve individuals, whole sporozoite (SPZ) vaccine efficacy in malaria-endemic settings has been suboptimal. Vaccine hypo-responsiveness due to previous malaria exposure has been posited as responsible, indicating the need for SPZ vaccines of increased immunogenic...

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Detalles Bibliográficos
Autores principales:	Duszenko, Nikolas, van Schuijlenburg, Roos, Chevalley-Maurel, Severine, van Willigen, Danny M., de Bes-Roeleveld, Laura, van der Wees, Stefanie, Naar, Chanel, Baalbergen, Els, Heieis, Graham, Bunschoten, Anton, Velders, Aldrik H., Franke-Fayard, Blandine, van Leeuwen, Fijs W. B., Roestenberg, Meta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500441/ https://www.ncbi.nlm.nih.gov/pubmed/37720224 http://dx.doi.org/10.3389/fimmu.2023.1204606

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