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GATA1 deletion in human pluripotent stem cells increases differentiation yield and maturity of neutrophils

Human pluripotent stem cell (hPSC)-derived tissues can be used to model diseases in cell types that are challenging to harvest and study at-scale, such as neutrophils. Neutrophil dysregulation, specifically neutrophil extracellular trap (NET) formation, plays a critical role in the prognosis and pro...

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Detalles Bibliográficos
Autores principales:	Harper, Thomas C., Oberlick, Elaine M., Smith, Tomas J., Nunes, Duncan E., Bray, Mark-Anthony, Park, Seonmi, Driscoll, Corey D., Mowbray, Sarah F., Antczak, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500457/ https://www.ncbi.nlm.nih.gov/pubmed/37720099 http://dx.doi.org/10.1016/j.isci.2023.107804

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