Assessing the Role of Trypsin in Quantitative Plasma and Single-Cell Proteomics toward Clinical Application

[Image: see text] Mass spectrometry-based bottom-up proteomics is rapidly evolving and routinely applied in large-scale biomedical studies. Proteases are a central component of every bottom-up proteomics experiment, digesting proteins into peptides. Trypsin has been the most widely applied protease...

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Detalles Bibliográficos
Autores principales: Woessmann, Jakob, Petrosius, Valdemaras, Üresin, Nil, Kotol, David, Aragon-Fernandez, Pedro, Hober, Andreas, auf dem Keller, Ulrich, Edfors, Fredrik, Schoof, Erwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500548/
https://www.ncbi.nlm.nih.gov/pubmed/37639361
http://dx.doi.org/10.1021/acs.analchem.3c02543

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