Bacillus Calmette-Guérin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial

BACKGROUND: Recurrences of herpes simplex virus (HSV) in the orofacial region (herpes labialis or cold sores) impact quality-of-life. We aimed to study whether the bacille Calmette-Guérin (BCG) vaccine can attenuate cold sore recurrences through off-target immunomodulatory effects. METHODS: In this...

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Detalles Bibliográficos
Autores principales: Pittet, Laure F., Moore, Cecilia L., McDonald, Ellie, Barry, Simone, Bonten, Marc, Campbell, John, Croda, Julio, Dalcolmo, Margareth, Davidson, Andrew, Douglas, Mark W., Gardiner, Kaya, Gwee, Amanda, Jardim, Bruno, Lacerda, Marcus V.G., Lucas, Michaela, Lynn, David J., Manning, Laurens, de Oliveira, Roberto D., Perrett, Kirsten P., Prat-Aymerich, Cristina, Richmond, Peter C., Rocha, Jorge L., Rodriguez-Baño, Jesus, Warris, Adilia, Wood, Nicholas J., Messina, Nicole L., Curtis, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500555/
https://www.ncbi.nlm.nih.gov/pubmed/37719417
http://dx.doi.org/10.1016/j.eclinm.2023.102203

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