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Salmonella meningitis in a young child from Pakistan: a case report

BACKGROUND: Salmonella meningitis is a rare but serious complication of Salmonella infection, primarily affecting infants, children, and immunocompromised individuals. CASE PRESENTATION: We present a case of a two-and-a-half-year-old Asian boy who developed Salmonella meningitis along with pneumonia...

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Autores principales: Majeed, Imad, Khan, Sami Ullah, Khan, Zaraq Rashid, Hayat, Sabawoon, Ullah, Ihtisham, Ali, Asim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500717/
https://www.ncbi.nlm.nih.gov/pubmed/37705001
http://dx.doi.org/10.1186/s13256-023-04128-0
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author Majeed, Imad
Khan, Sami Ullah
Khan, Zaraq Rashid
Hayat, Sabawoon
Ullah, Ihtisham
Ali, Asim
author_facet Majeed, Imad
Khan, Sami Ullah
Khan, Zaraq Rashid
Hayat, Sabawoon
Ullah, Ihtisham
Ali, Asim
author_sort Majeed, Imad
collection PubMed
description BACKGROUND: Salmonella meningitis is a rare but serious complication of Salmonella infection, primarily affecting infants, children, and immunocompromised individuals. CASE PRESENTATION: We present a case of a two-and-a-half-year-old Asian boy who developed Salmonella meningitis along with pneumonia and respiratory failure. Initially, he experienced symptoms of loose motions, fever, and irritability, which progressed to neck stiffness and brisk reflexes. Cerebrospinal fluid (CSF) analysis confirmed Salmonella typhi in the CSF. Due to the worsening condition, the patient was admitted to the intensive care unit, intubated, and switched to meropenem as the antibiotic of choice after an initial empiric therapy with ceftriaxone and vancomycin. With appropriate treatment, the patient showed significant improvement, including resolution of fever and respiratory symptoms. CONCLUSION: Management of Salmonella meningitis is often challenging primarily because of the fact that the empiric therapy for meningitis may not always provide coverage to the multi-drug resistant Salmonella species found in South Asia. Prompt administration of appropriate antibiotics based on sensitivity testing is crucial for successful management. This case emphasizes the importance of early recognition and effective management of this uncommon yet severe complication of Salmonella infection.
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spelling pubmed-105007172023-09-15 Salmonella meningitis in a young child from Pakistan: a case report Majeed, Imad Khan, Sami Ullah Khan, Zaraq Rashid Hayat, Sabawoon Ullah, Ihtisham Ali, Asim J Med Case Rep Case Report BACKGROUND: Salmonella meningitis is a rare but serious complication of Salmonella infection, primarily affecting infants, children, and immunocompromised individuals. CASE PRESENTATION: We present a case of a two-and-a-half-year-old Asian boy who developed Salmonella meningitis along with pneumonia and respiratory failure. Initially, he experienced symptoms of loose motions, fever, and irritability, which progressed to neck stiffness and brisk reflexes. Cerebrospinal fluid (CSF) analysis confirmed Salmonella typhi in the CSF. Due to the worsening condition, the patient was admitted to the intensive care unit, intubated, and switched to meropenem as the antibiotic of choice after an initial empiric therapy with ceftriaxone and vancomycin. With appropriate treatment, the patient showed significant improvement, including resolution of fever and respiratory symptoms. CONCLUSION: Management of Salmonella meningitis is often challenging primarily because of the fact that the empiric therapy for meningitis may not always provide coverage to the multi-drug resistant Salmonella species found in South Asia. Prompt administration of appropriate antibiotics based on sensitivity testing is crucial for successful management. This case emphasizes the importance of early recognition and effective management of this uncommon yet severe complication of Salmonella infection. BioMed Central 2023-09-14 /pmc/articles/PMC10500717/ /pubmed/37705001 http://dx.doi.org/10.1186/s13256-023-04128-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Majeed, Imad
Khan, Sami Ullah
Khan, Zaraq Rashid
Hayat, Sabawoon
Ullah, Ihtisham
Ali, Asim
Salmonella meningitis in a young child from Pakistan: a case report
title Salmonella meningitis in a young child from Pakistan: a case report
title_full Salmonella meningitis in a young child from Pakistan: a case report
title_fullStr Salmonella meningitis in a young child from Pakistan: a case report
title_full_unstemmed Salmonella meningitis in a young child from Pakistan: a case report
title_short Salmonella meningitis in a young child from Pakistan: a case report
title_sort salmonella meningitis in a young child from pakistan: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500717/
https://www.ncbi.nlm.nih.gov/pubmed/37705001
http://dx.doi.org/10.1186/s13256-023-04128-0
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